Hanneke Hemmink

Personal Information
Staff picture Full name Hanneke Hemmink
Position
Email h.hemmink@cgiar.org
Telephone +254-204223412
Profile

Hanneke Hemmink has a background in veterinary medicine and has an interest in all aspects of infectious disease, immunology and vaccinology. She worked in clinical farm animal medicine in the UK and completed her Msc and PhD at the Roslin Institute, where she worked on immunology against the protozoan parastites Theileria annulata and Theileria parva. She than worked on porcine immunology at the Pirbright institute on the BBSRC SLOLA swine influenza dynamics project; linking transmission, evolutionary dynamics, pathogenesis and immunity in pigs. After working with the Centre of Livestock genetics and Health (CTLGH) for two years, she is now part of the animal and human health department at ILRI. Back in the field of immunology/vaccinology, working towards the development of a subunit vaccine against African Swine Fever. 

Publications

Hemmink JD, Whittaker C., Shelton H., Methods in Molecular Biology, Influenza Virus: Methods & Protocols, Springer. Book chapter: Animal models in influenza research.

Tungatt K, Dolton G, Morgan SB, Attaf M, Fuller A, Whalley T, Hemmink JD, Porter E, Szomolay B., Montoya M., Hammond J.A., Miles J.J., Cole D.K. Townsend A., Bailey M., Rizkalla P., Charleston B., Tchilian E., Sewell A.K. Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in theBrabaham inbred pig. 2018 PLoS Pathog 14(5): e1007017.

Schwartz JC, Hemmink JD, Graham SP, Tchilian E, Hammer SE, Ho C, Hammond JA. The MHC homozygous inbred Babraham pig as a resource for veterinary and translational medicine. HLA 2018 doi: 10.1111/tan.13281

Morgan SB, Holzer B, Hemmink JD, Salguero F, Schwartz, J., Agatic, G, Cameroni E., Porter, E, Rijal P, Townsend A, Charleston B, Corti D, Tchilian E. Therapeutic administration of broadly neutralizing FI6 antibody in a pig influenza model. Frontiers immunology 2018; 9:865.

Hemmink JD, Sitt T, Pelle R, de Klerk-Lorist L, Shiels B, Toye PG, Morrison IM, Weir, W.  Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci. International journal of Parasitology 2018 48 (3-4):287-296

Hemmink JD*, Morgan SB*, Aramouni  M, Everett H, Salguero F, Canini L, Porter E, Chase-Topping M, Beck K, MacLoughlin R, Carr V, Brown I, Bailey M, Woolhouse M, Brookes S,  Charleston B , Tchilian E. Distinct immune responses and virus shedding in pigs following aerosol, intranasal and contact infection with pandemic swine influenza A virus, A(H1N1)09. Veterinary Research 2016 47:103

Morgan SB*, Hemmink JD*, Porter E, Harley R, Shelton H, Aramouni M, Everett HE, Brookes SM, Bailey M, Townsend AM, Charleston B, Tchilian E. Aerosol delivery of a candidate universal vaccine reduces viral load in pigs challenged with pandemic H1N1 virus. Journal of immunology 2016 196 (12):5014-5023

Hemmink JD, Weir W, MacHugh ND, Graham SP, Patel E, Paxton E, Shiels B, Toye PG, Morrison WI and Pelle R.  Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva . International journal of Parasitology 2016 46 (8):495-506

Bishop RP*,  Hemmink JD* Morrison WI, Weir W,  Toye P, Sitt T,  Spooner PR,  Musoke AJ,  Skilton RA and  Odongo DO.  The African buffalo parasite Theileria sp. (buffalo) can infect and immortalize cattle leukocytes and encodes conserved and divergent orthologues of T. parva antigen genes. International Journal for Parasitology: Parasites and Wildlife 2015 29; 4(3):333-42

Morrison WI, Connelley T, Hemmink JD, MacHugh ND. Understanding the basis of parasite strain-restricted immunity to Theileria parva . Annu Rev Anim Biosci. 2015;3:397-418

*joint first authorship

 

 

My ILRI work/Web address