Selecting efficient farm-level antimicrobial stewardship interventions from a One Health perspective


This project uses a One Health approach to assess which farm-level antimicrobial use interventions are most efficient to prevent the development and transmission of antimicrobial resistance in Senegal.

The project provides explicit impact estimates and ranking for a range of farm-level antimicrobial resistance interventions in Senegal, highlighting where future research could be most valuable in understanding intervention efficiency from a One Health perspective.


  • Establish a consortium and international knowledge hub for information dissemination.
  • Identify the most important antimicrobial resistance intervention assessment needs and outcome/impact measures.
  • Use case studies to assess the impact of previous antimicrobial use policies and farm-level interventions. 
  • Quantify the transmission dynamics of antimicrobial resistance and estimate the impact of antimicrobial use and antimicrobial resistance scenarios on people, animals and the environment. 
  • Use case studies to establish the cost-effectiveness of specific interventions across the health, agriculture and environment sectors.

Expected outcomes

  • Policymakers are supported to allocate adequate finances towards national action plans to tackle antimicrobial resistance.
  • Modelling resources are made available for future One Health interventions to help in assessing spillover of antimicrobial resistance into the environment as a result of human activities.
  • Interventions to reduce antimicrobial resistance work effectively across the One Health spectrum of human, animal and environment health.
  • Development of an adaptable, open access One Health tool.
  • Improved sector and transnational collaboration to promote information sharing.