Genomic surveillance of Rift Valley fever virus

Abstract

Pathogen genomic data are critical in the development of vaccines and diagnostics. Currently, there are only a handful of Rift Valley fever virus (RVFV) genomic sequence data.

For a long time, generation of genomic data for RVFV has relied on culture of the virus. This procedure often requires highly skilled personnel to handle the pathogenic virus, and is labour-intensive and time consuming (minimum 14 days).

We designed a simple and cost-effective method that enriches the virus particles directly from clinical samples. This enrichment procedure targets the virus, which can then be sequenced in a near real-time manner devoid of cell culture enrichment.

Citation

Juma, J. and Limbaso, S.K. 2024. Genomic surveillance of Rift Valley fever virus. Poster presented at the Independent Science for Development Council (ISDC) Share Fair, Nairobi, Kenya, 13–16 February 2024. Nairobi, Kenya: ILRI.

Authors

  • Juma, John
  • Limbaso, S.K.