Ruminant cluster CD41/CD61

Journal Article
Published on
byElsevier

Abstract

After analysis of flowcytometry data on bovine and ovine cells and immunoprecipitation studies, a cluster of seven MAbs-CAPP2 (3W-232), IL-A164 (M430), IL-A166 (3W-226), IVA30 (3W-069), IVA31 (3W-468), IVA38 (3W-349) and IVA125 (3W 528) - was shown to detect bovine and ovine CD41/Cd61 (also known as alpha IIb beta 3 integrin and GpIIb/IIIa). One additional MAb from the workshop panel, Co-20A1 (3W-386), was shown to react with the ovine GpIIb/IIIa molecule only (Pintado et al., 1995; Mateo et al., 1996a). MAb Co-35E4, not submitted to the workshop, also precipitated the platelet integrin and cross-reacted with several species (Pintado et al., 1995)

Citation

Veterinary Immunology and Immunopathology;52(4): 251-253

Authors

  • Mateo, A.
  • Pintado, C.O.
  • Lastra, J.de la
  • Dusinsky, R.
  • Simon, M.
  • Naessens, Jan
  • Llanes, D.

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