Samuel O. Oyola

Samuel O. Oyola

Senior Scientist: Molecular Biologist and Head of Genomics

Samuel Oyola is ILRI’s Specialist Scientist in Genomics and Molecular Biology. He holds a PhD in Molecular and Cellular Biology from the University of Cambridge. Before joining ILRI, he studied functional genomics of Leishmaniasis and host-parasite interaction as a postdoctoral fellow at the University of York. He then took a Scientist position at the Wellcome Trust Sanger Institute, Cambridge UK, where he worked on malaria; developing and applying high throughput genomic technologies to study natural genetic variations in malaria parasite populations. He developed novel molecular tools that enable application and translation of genomic technologies into basic healthcare and public health applications. At ILRI, Samuel is using his experience and expertise in modern genomics, biotechnology and molecular biology to study several aspects of animal and human health. Under epidemiology, Samuel is using modern genomic and bioinformatic tools to study epidemiology of rift valley fever virus (RVF), African swine fever virus (ASFV), Newcastle disease virus (NDV) and Peste des petits ruminants virus (PPRV), SARS-CoV-2 (COVID-19) and Climate-aggravated infectious diseases such as those caused by Arboviruses. Under vaccine development, Samuel is employing his immunogenetics expertise to develop anti-east coast fever vaccine by profiling antibody immune (B-cell receptor repertoire) responses to candidate vaccine immunizations.  Samuel is also actively involved in developing Genomic Surveillance capacity in Africa.

My Projects


Boosting Uganda’s investment in livestock development


Co-infection with Rift Valley fever virus, Brucella spp. and Coxiella burnetii in humans and animals in Kenya: Disease burden and ecological factors

My Publications

Widening geographic range of Rift Valley fever disease clusters associated with climate change in East Africa

  • Situma, S.
  • Nyakarahuka, L.
  • Omondi, E.
  • Mureithi, M.
  • Mweu, M.M.
  • Muturi, M.
  • Mwatondo, A.
  • Dawa, J.
  • Konongoi, L.
  • Khamadi, S.
  • Clancey, E.
  • Lofgren, E.
  • Osoro, E.
  • Ngere, I.
  • Breiman, R.F.
  • Bakamutumaho, B.
  • Muruta, A.
  • Gachohi, J.
  • Oyola, Samuel O.
  • Njenga, M.K.
  • Singh, D.

Isolation and phylogenetic characterization of arboviruses circulating among phlebotomine sandflies in parts of North Rift, Kenya

  • Koskei, E.
  • Langat, S.
  • Mutisya, J.
  • Mulwa, F.
  • Lutomiah, J.
  • Koka, H.
  • Oyola, Samuel O.
  • Waihenya, R.
  • Mabeya, S.N.
  • Sang, R.

Save lives in the next pandemic: ensure vaccine equity now

  • Carlson, C.
  • Becker, D.
  • Happi, C.
  • O'Donoghue, Z.
  • Oliveira, T. de
  • Oyola, Samuel O.
  • Poisot, T.
  • Seifert, S.
  • Phelan, A.

Metagenomic characterization of poultry cloacal and oropharyngeal swabs in Kenya reveals bacterial pathogens and their antimicrobial resistance genes

  • Panyako, P.M.
  • Ommeh, S.C.
  • Kuria, S.N.
  • Lichoti, J.K.
  • Musina, J.
  • Nair, V.
  • Nene, Vishvanath
  • Munir, M.
  • Oyola, Samuel O.

Metagenomic characterization reveals virus coinfections associated with Newcastle disease virus among poultry in Kenya

  • Panyako, P.M.
  • Ommeh, S.C.
  • Kuria, S.N.
  • Lichoti, J.K.
  • Musina, J.
  • Nair, V.
  • Nene, Vishvanath M.
  • Oyola, Samuel O.
  • Munir, M.

A pan-African pathogen genomics data sharing platform to support disease outbreaks

  • Christoffels, A.
  • Mboowa, G.
  • Heusden, P. van
  • Makhubela, S.
  • Githinji, G.
  • Mwangi, S.
  • Onywera, H.
  • Nnaemeka, N.
  • Amoako, D.G.
  • Olawoye, I.
  • Diallo, A.
  • Mbala-Kingebeni, P.
  • Oyola, Samuel O.
  • Adu, B.
  • Mvelase, C.
  • Ondoa, P.
  • Dratibi, F.A.
  • Sow, A.
  • Gumede, N.
  • Tessema, S.K.
  • Ouma, A.O.
  • Tebeje, Y.K.