In the early 1900s, cattle herds across South Africa were devastated by a new livestock disease. Today, more than 100 years later, that disease is called East Coast fever, and despite scientists' best efforts to control it, the disease continues to devastate cattle and livelihoods across the dozen African countries where it is endemic.
In this episode, presenters Elliot Carleton and Brenda Coromina speak with ILRI scientist Vish Nene as they examine what makes East Coast fever such a devastating disease, and more importantly, how modern vaccines may be able to address it.
0:58 History of East Coast fever
2:16 A neglected disease
3:09 Why is East Coast fever so dangerous?
4:56 East Coast fever's impact on livelihoods
5:46 And what about vaccines?
8:20 But there's one big problem...
8:52 The Muguga cocktail
9:42 The benefits of vaccination
11:47 Remaining challenges with current vaccines
13:10 A subunit vaccine for the future